Betrayal can defined as anything that is an insult to the organ of trust. "Insult" is used here in a medical sense, of something that causes shock, stress, injury or the like to an organ. The organ must recover in order to trust again. The "organ of trust" can be taken as a metaphor for the set of different receptivities or functions within a person or a person's body. It may be that the brain itself is an organ of trust.